Why we Slay

The Nicholas Lab is a brand new research group in the Department of Molecular Biology & Biochemistry at the University of California, Irvine. Our lab blurs the boundaries between the disciplines of immunology, metabolism, and endocrinology to discover the mechanisms that drive endocrine disease. We are actively recruiting motivated and creative students to break the confines of disciplinary science and begin new frontiers to determine how the immune system interacts with metabolism and reproduction using a combination of molecular and cellular biology, transcriptomics, transgenic mouse models, cytokine profiling, and flow cytometry. Our ambition is to create working models of immunologic processes that drive disease to pinpoint novel therapeutic interventions for type 2 diabetes and polycystic ovary syndrome.

The Nicholas Lab believes “Happy People do Great Science!” and embraces the journey of scientific discovery. We are dedicated to cultivating an inclusive, collaborative, and creative research community that encourages bold ideas and supports everyone being their authentic self. We are one a mission to make the world better one experiment at a time, but we don’t forget to have fun along the way.

Wanna get in on the action? Send inquiries about joining our group or general questions can to thenicholaslab@gmail.com.


“Understand how excess nutrients impact immunological function in health and disease and leverage this knowledge to develop effective immunotherapy to treat type 2 diabetes and polycystic ovary syndrome”


The Nicholas Lab mission is two parts:

  1. Advance the standard of care for type 2 diabetes and polycystic ovary syndrome
  2. Diversify the Biomedical Science workforce with brilliant scientists from with a wealth of different lived experiences

“Happy People Do Great Science”

Science does not happen in a vacuum. It is done by people. Fully supported trainees develop the confidence to take creative risks and do bold science.


“Make discoveries by doing what no one else is willing to try”

In the Nicholas lab, we are not afraid to develop new approaches and tackle unanswered questions just because it will be difficult. We have the confidence to fail and troubleshoot until we figure it out.